An sanar da bullar COVID-19 ta farko a Afirka a Masar a ranar 14 ga Fabrairun shekarar 2020.[1][2] An aiwatar da matakan rigakafi da yawa a cikin ƙasashe daban-daban a Afirka, gami da hana tafiye-tafiye, soke jirgin sama, soke taron,[3] rufe makarantu, da rufe kan iyaka.[4] Sauran matakan da za a dauka da takaita yaduwar cutar sun haɗa da dokar hana fita, ƙulle-ƙulle, da kuma tilasta sanya abin rufe fuska . Kwayar cutar ta bazu ko'ina cikin nahiyar. Lesotho, ƙasa ta ƙarshe mai cin gashin kanta ta Afirka da ta kasance ba ta da kwayar cutar, ta ba da rahoton bullar cutar a ranar 13 ga Mayu 2020.[5][6]